EVALUATION OF SIMPLE TESTS FOR DETECTION OF HIV ANTIBODIES - ANALYSIS OF INTEROBSERVER VARIATION IN TANZANIA

被引:1
|
作者
JORGENSEN, A
SHAO, J
MASELLE, S
YANGI, E
THOMSEN, A
MATUNDA, S
BYGBJERG, I
GOTZSCHE, P
SVENDSEN, J
SKINHOJ, P
FABER, V
机构
[1] RIGSHOSP,DEPT INFECT DIS,DK-2100 COPENHAGEN,DENMARK
[2] MUHIMBILI MED CTR,DEPT MICROBIOL,DAR ES SALAAM,TANZANIA
[3] MUHIMBILI MED CTR,DEPT IMMUNOL,DAR ES SALAAM,TANZANIA
关键词
D O I
10.3109/00365549009027049
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
200 sera were tested for HIV antibodies with different tests in Tanzania. The results were interpreted by 5 different observers with different laboratory experience. There was considerable variation between observers and between testing methods. HIV-Chek was easiest to perform with little interobserver variation, but a few probably false negative readings were seen. Serodia gave many false positives. Western Blots gave more diverging results due to indeterminate sera and lack of training. HIV-Chek seems best when time, facilities, and training are limited and if combined with Serodia false negative results can be excluded. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码:283 / 285
页数:3
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