COMPARATIVE-STUDY OF ADENOVIRUSES WITH MONOCLONAL-ANTIBODIES

被引：2
|
作者：
DEPAIVA, TM [1 ]
TAKIMOTO, S [1 ]
ISHIDA, MA [1 ]
DESOUZA, MCO [1 ]
ISHIMARU, T [1 ]
NEUMANN, J [1 ]
KALIL, J [1 ]
机构：
[1] UNIV SAO PAULO,FAC MED,IMUNOL TRANSPLANTES LAB,SAO PAULO,BRAZIL
来源：
REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO | 1992年 / 34卷 / 01期
关键词：
ADENOVIRUS; SPECIES SPECIFIC; MONOCLONAL ANTIBODIES; ADENOVIRUS-4; ANTIGENIC RELATIONSHIP;
D O I：
10.1590/S0036-46651992000100004
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The obtainment of monoclonal antibodies for adenovirus species 4(Ad4) is described. The specificities of selected monoclonal antibodies were determined by means of viral neutralization test in cell culture, immunofluorescence and Enzyme-Linked Immunosorbent Assay (ELISA), in the presence of the following species of human adenovirus: 1, 2, 5 (subgenus C), 4 (subgenus E), 7 and 16 (subgenus B) and 9 (subgenus D). Two monoclonal antibodies species specific to adenovirus 4 (1CIII and 3DIII) and one monoclonal antibody that cross reacted with adenovirus species 4 and 7 (2HIII) were obtained.
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页码：19 / 26
页数：8
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