Interstitial Lung Disease in Sjogren's Syndrome

被引：0

作者：

Nikpour, Mandana ^{[1
,2
]}

Proudman, Susanna M. ^{[3
]}

Goh, Nicole S. ^{[4
]}

Moutsopoulos, Haralampos M. ^{[5
]}

机构：

[1] Univ Melbourne, Dept Med, Melbourne, Vic, Australia

[2] St Vincents Hosp, Dept Rheumatol, Melbourne, Vic, Australia

[3] Royal Adelaide Hosp, Dept Rheumatol, Adelaide, SA, Australia

[4] Austin Hosp, Dept Resp Med, Melbourne, Vic, Australia

[5] Natl Univ Athens, Sch Med, Dept Pathophysiol, Athens, Greece

来源：

CURRENT RHEUMATOLOGY REVIEWS | 2010年 / 6卷 / 02期

关键词：

Sjogren's syndrome; interstitial lung disease; lymphoproliferative;

D O I：

10.2174/157339710791330687

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Sjogren's syndrome (SS), whether primary, or secondary to other autoimmune rheumatic diseases, is classically associated with the sicca complex of keratoconjunctivits and xerostomia. However, extraglandular manifestations are also relatively common, affecting up to 25% of patients. In this article, we discuss respiratory system involvement in SS, with a focus on interstitial lung disease (ILD). We review the histopathologic variants, clinical features, diagnosis and treatment of SS-ILD. Novel and emerging diagnostic and prognostic biomarkers for SS-ILD are also discussed. We offer an approach to the management of SS-ILD including possible goals of therapy. We conclude by highlighting areas for future research.

引用

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页码：127 / 137

页数：11

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