COLLATERAL PROJECTIONS OF SINGLE NEURONS IN THE NUCLEUS RAPHE MAGNUS TO BOTH THE SENSORY TRIGEMINAL NUCLEI AND SPINAL-CORD IN THE RAT

被引：17
|
作者：
LI, YQ [1 ]
TAKADA, M [1 ]
SHINONAGA, Y [1 ]
MIZUNO, N [1 ]
机构：
[1] KYOTO UNIV,FAC MED,DEPT MORPHOL BRAIN SCI,KYOTO 60601,JAPAN
来源：
BRAIN RESEARCH | 1993年 / 602卷 / 02期
关键词：
NUCLEUS RAPHE MAGNUS; PAIN; NOCICEPTION; SEROTONIN; SENSORY TRIGEMINAL NUCLEI; SPINAL CORD; RAT;
D O I：
10.1016/0006-8993(93)90698-M
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
After injecting Diamidino yellow and Fast blue respectively into the sensory trigeminal nuclei and spinal cord, we observed doubly labeled cells in the nucleus raphe magnus (NRM). Combining the fluorescent retrograde double labeling with serotonin (5-HT) immunofluorescence histochemistry, we further found that about 30% of the doubly labeled NRM neurons showed 5-HT-like immunoreactivity (5-HT-LI). Such 5-HT-LI NRM neurons may modulate nociceptive activities simultaneously in the sensory trigeminal nuclei and spinal cord by sending axon collaterals to these regions.
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页码：331 / 335
页数：5
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