TRIFLUOROETHYL PHENYL IODONIUM TRIFLATE - MODIFIED PREPARATION AND N-TRIFLUOROETHYLATION OF AMINO-ALCOHOLS

被引：14

作者：

MONTANARI, V

RESNATI, G

机构：

[1] CNR-Centro Studio Sostanze Organiche Naturali, Politecnico, 20131 Milano

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 43期

关键词：

D O I：

10.1016/0040-4039(94)80037-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title iodinane 3 (Umemoto's FMITS-1) is prepared in two steps from the readily accessible CF3CH2ICl2 (1). 1 and 2 eq. of CF3COOAg react in CFCl2CF2Cl (FC 113) to give CF3CH2(OCOCF3)(2) (2) which is converted into 3 by the known method. With this modification chlorine and nontoxic FC 113 replace 60-80% H2O2 and trifluoroacetic anhydride as the oxidant and the solvent, respectively, in the synthesis of the intermediate 2. The N-trifluoroethylation of some aminoalcohols by FMITS-1 is also reported.

引用

页码：8015 / 8018

页数：4

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