RODS, CONES AND CALCIUM

被引：8
|
作者：
MCNAUGHTON, PA
机构：
[1] Department of Physiology, King's College London, London
来源：
CELL CALCIUM | 1995年 / 18卷 / 04期
关键词：
D O I：
10.1016/0143-4160(95)90024-1
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
A transduction cascade in the outer segments of vertebrate photoreceptors amplifies the visual signal, resulting in the metabolism of cGMP and the closure of ionic channels. The intracellular calcium concentration declines after a light response, and this decline is the key regulator responsible for controlling the gain of the transduction cascade, Calcium turnover in the outer segment is determined by three processes: influx through light-sensitive channels; buffering within the outer segment; and extrusion by a Na/Ca,K exchange mechanism.
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页码：275 / 284
页数：10
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