INCREASED LEVELS OF NGF IN SERA OF SYSTEMIC LUPUS-ERYTHEMATOSUS PATIENTS

被引：119
|
作者：
BRACCILAUDIERO, L
ALOE, L
LEVIMONTALCINI, R
GALEAZZI, M
SCHILTER, D
SCULLY, JL
OTTEN, U
机构：
[1] UNIV BASEL, DEPT PHYSIOL, VESALGASSE 1, CH-4051 BASEL, SWITZERLAND
[2] CNR, INST NEUROBIOL, ROME, ITALY
[3] UNIV SIENA, DEPT PHYSIOL, I-53100 SIENA, ITALY
来源：
NEUROREPORT | 1993年 / 4卷 / 05期
关键词：
SYSTEMIC LUPUS ERYTHEMATOSUS; NERVE GROWTH FACTOR; ELISA; AUTOIMMUNITY;
D O I：
10.1097/00001756-199305000-00025
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
USING a specific enzyme-linked immunosorbent assay (ELISA) for human nerve growth factor (NGF), serum levels in patients with systemic lupus erythematosus (SLE) were measured. We found a consistent increase in NGF levels in SLE patients compared with controls. A good correlation exists between serum NGF level and severity of clinical manifestation. We hypothesize that NGF might play a role in the pathogenesis of autoimmune disorders such as SLE.
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收藏
页码：563 / 565
页数：3
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