THE VACCINE-ADVERSE-EVENT-REPORTING-SYSTEM (VAERS)

被引：329

作者：

CHEN, RT ^{[1
]}

RASTOGI, SC ^{[1
]}

MULLEN, JR ^{[1
]}

HAYES, SW ^{[1
]}

COCHI, SL ^{[1
]}

DONLON, JA ^{[1
]}

WASSILAK, SG ^{[1
]}

机构：

[1] US FDA,CTR BIOL EVALUAT & RES,ROCKVILLE,MD 20857

来源：

VACCINE | 1994年 / 12卷 / 06期

关键词：

VACCINATION; IMMUNIZATION; ADVERSE REACTIONS; PRODUCT SURVEILLANCE; POSTMARKETING;

D O I：

10.1016/0264-410X(94)90315-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Immunizations against most vaccine-preventable diseases will be needed indefinitely unless the disease is eradicated. Public acceptance of immunizations may be threatened as vaccine coverage increases and disease decreases, however, due to the increase in both causally and coincidentally related vaccine adverse events. The post-marketing surveillance for such events in the USA in response to the mandatory reporting requirements of the National Childhood Injury Act of 1986. While VAERS has many methodological limitations intrinsic to such systems, it can play an important role in helping to monitor vaccine safety and maintain public confidence in immunizations.

引用

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页码：542 / 550

页数：9

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