Acute renal failure is a rare, but severe complication of measles. In this article, a case with acute renal failure resulting from measles is presented. A 20-year-old male patient suffering from high fever, sore throat, and eruptions was diagnosed as measles via physical examination and laboratory tests. On the tenth day of his hospitalization, he suffered from nausea and vomiting. He became unconscious, his urinary output was decreased and he developed periorbital edema. Serum urea and creatinin levels were increased. Analyzing his laboratory results and with the help of sign and symptoms, the case was diagnosed as acute renal failure resulting from measles. Hemodialysis cured the patient and he was discharged. The clinical and laboratory findings should be carefully followed up in case the patient with measles may develop acute renal failure.