Preservation of endurance and mobility during allogeneic hematopoietic cell transplantation (alloHCT)

As a consequence of alloHCT, various side effects occur which lead to the decline of physical capability. The aim of this randomized pilot study (n = 13) was the preservation of the physical capability through endurance exercise or balance training and to investigate adaption to the new recommendations for assessment methods. Overall, there was a reduction of the physical capability despite therapeutic exercises. Whereas the assessment methods were well tolerated, the toxic therapy and the therapy-induced immobilization seemed to have altered normal cardiovascular und musculoskeletal training adaption and led to the weakness of aerobic capacity.