SYNTHESIS AND CHARACTERIZATION OF SOME NEW FERROCENE-CONTAINING RIFAMYCINS

被引：9
|
作者：
SCUTARU, D
MAZILU, I
TATARU, L
VATA, M
LIXANDRU, T
机构：
[1] Department of Organic Chemistry, Polytechnic Institute of Jassy, 6600 Jassy, Str. 23 August
来源：
JOURNAL OF ORGANOMETALLIC CHEMISTRY | 1991年 / 406卷 / 1-2期
关键词：
D O I：
10.1016/0022-328X(91)83185-7
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Eleven new ferrocene-containing rifamycins have been obtained by the condensation of 3-formylrifamycin SV with hydrazides of some S-modified, ferrocene-containing thioglycolic acids. The products were characterized by their UV spectra and TLC. The observed biological activity was lower than that of Rifampicin on Gram-positive bacteria, and insignificant towards Gram-negative ones.
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页码：183 / 187
页数：5
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