Cancrum oris cases are occasionally treated in various hospitals in Kenya, Despite this, only one case has been reported in literature, Besides, no epidemiological or treatment studies of cancrum oris has been carried out in Kenya. We report an unusual case of a 17 year old Kenyan female with oral cutaneous fistula and tissue atrophy on the left cheek following cancrum oris infection in childhood, Since most cancrum oris cases are a sequela of acute necrotizing gingivitis (ANG), prevention of cancrum oris can be achieved by early and prompt remedial measures once a diagnosis of ANG is established, Failure to do this might lead to cancrum oris with its attendant disfiguring complications pome of which might be impossible to treat in developing countries where the requisite personnel is lacking or inadequate.