FALL SEVERITY AND BONE-MINERAL DENSITY AS RISK-FACTORS FOR HIP FRACTURE IN AMBULATORY ELDERLY

被引:443
|
作者
GREENSPAN, SL
MYERS, ER
MAITLAND, LA
RESNICK, NM
HAYES, WC
机构
[1] BETH ISRAEL HOSP,DEPT MED,DIV GERONTOL,BOSTON,MA 02215
[2] BETH ISRAEL HOSP,DEPT ORTHOPAED SURG,ORTHOPAED BIOMECH LAB,BOSTON,MA 02215
[3] BETH ISRAEL HOSP,CHARLES A DANA RES INST,BOSTON,MA 02215
[4] HARVARD UNIV,SCH MED,BOSTON,MA 02115
[5] BRIGHAM & WOMENS HOSP,DIV GERONTOL,BOSTON,MA 02115
[6] VET ADM MED CTR W ROXBURY,CTR GERIATR RES EDUC & CLIN,BOSTON,MA 02132
来源
关键词
D O I
10.1001/jama.271.2.128
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective.-To determine the relative importance of fall characteristics, body habitus, and femoral bone mineral density (BMD) in predicting hip fracture in community-dwelling elderly. Design.-Prospective case-control study. Setting.-Community-based academic hospital. Participants.-A total of 149 ambulatory, community-dwelling fallers (126 women, 23 men) aged 65 years and older, including 72 case patients (fallers with hip fracture) and 77 control fallers (fallers with no hip fracture). Main Outcome Measures.-Fall characteristics, body habitus, femoral BMD. Results.-Significant and independent risk factors for hip fracture in both sexes were direction of the fall (adjusted odds ratio [OR], 5.7; 95% confidence interval [CI], 2.3 to 14.0; P<.001); femoral neck BMD (a decrease of 1 SD; adjusted OR, 2.795% CI, 1.6 to 4.6; P<.001); potential energy of the fall (an increase of 1 SD; adjusted OR, 2.8; 95% CI, 1.5 to 5.2; P<.001); and body mass index (a decrease of 1 SD; adjusted OR, 2.2; 95% CI, 1.2 to 3.8; P<.01). Importantly, the OR for the fall direction was unaffected by the addition or removal of BMD from the model. Conclusions.-We conclude that among elderly fallers-in most of whom hip BMD is already less than the fracture threshold-fall characteristics and body habitus are important risk factors for hip fracture and touch on a domain entirely missed by knowledge of BMD. These data suggest new targets for preventive therapy. In addition to the maintenance of bone density, reductions in fall severity (eg, by use of trochanteric padding or enhancement of muscle strength) may provide additional strategies for prevention of hip fracture in this age group.
引用
收藏
页码:128 / 133
页数:6
相关论文
共 50 条
  • [21] Bone mineral density in Chinese elderly women with hip fracture
    Yang, RS
    Liu, TK
    Dorey, FJ
    Chieng, PU
    CALCIFIED TISSUE INTERNATIONAL, 1996, 58 (06) : 385 - 389
  • [22] THE EFFECT OF GYNECOLOGICAL RISK-FACTORS ON LUMBAR AND FEMORAL BONE-MINERAL DENSITY IN PERIMENOPAUSAL AND POSTMENOPAUSAL WOMEN
    TUPPURAINEN, M
    KROGER, H
    SAARIKOSKI, S
    HONKANEN, R
    ALHAVA, E
    MATURITAS, 1995, 21 (02) : 137 - 145
  • [23] BONE-MINERAL MASS IN HIP FRACTURE PATIENTS
    KARLSSON, MK
    JOHNELL, O
    NILSSON, BE
    SERNBO, I
    OBRANT, KJ
    BONE, 1993, 14 (02) : 161 - 165
  • [24] BONE-MINERAL DENSITY OF THE CALCANEUS PREDICTS HIP FRACTURE STRENGTH IN-VITRO
    BOUXSEIN, ML
    MYERS, ER
    COURTNEY, AC
    HAYES, WC
    JOURNAL OF BONE AND MINERAL RESEARCH, 1993, 8 : S255 - S255
  • [25] RADIOGRAPHIC OSTEOARTHRITIS OF THE HIP AND BONE-MINERAL DENSITY
    NEVITT, MC
    LANE, NE
    SCOTT, JC
    HOCHBERG, MC
    PRESSMAN, AR
    GENANT, HK
    CUMMINGS, SR
    ARTHRITIS AND RHEUMATISM, 1995, 38 (07): : 907 - 916
  • [27] SERUM UNDERCARBOXYLATED OSTEOCALCIN CORRELATES WITH HIP BONE-MINERAL DENSITY IN ELDERLY WOMEN
    SZULC, P
    ARLOT, M
    CHAPUY, MC
    DUBOEUF, F
    MEUNIER, PJ
    DELMAS, PD
    JOURNAL OF BONE AND MINERAL RESEARCH, 1994, 9 (10) : 1591 - 1595
  • [28] RISK-FACTORS FOR HIP FRACTURE
    KELSEY, JL
    HOFFMAN, S
    NEW ENGLAND JOURNAL OF MEDICINE, 1987, 316 (07): : 404 - 406
  • [29] RISK-FACTORS FOR HIP FRACTURE
    FARMER, M
    WALLACE, R
    WHITE, L
    MADANS, J
    HARRIS, T
    HUNTLEY, J
    AMERICAN JOURNAL OF EPIDEMIOLOGY, 1987, 126 (04) : 781 - 781
  • [30] RISK-FACTORS FOR HIP FRACTURE
    COOPER, C
    BARKER, DJP
    NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (12): : 814 - 815