EFFECT OF INMECARB ON ALCOHOL-CONSUMPTION AND STATE OF THE CYTOCHROME-P-450 SYSTEM OF THE LIVER AT DIFFERENT STAGES OF EXPERIMENTAL ALCOHOLISM IN RATS

被引：0
|
作者：
KHLOPUSHINA, GT
KASHEVSKAYA, OP
KAMPOVPOLEVOI, AB
机构：
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1990年 / 110卷 / 09期
关键词：
EXPERIMENTAL ALCOHOLISM; CHRONIC ALCOHOLIZATION; CYTOCHROME-P-450; SYSTEM; INMECARB;
D O I：
10.1007/BF00840289
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
One possible mechanism of depression of alcohol consumption may be by inhibiting the system of liver ethanol-oxidizing enzymes. The aim of this investigation was to study the effect of inmecarb, a new drug suggested for the treatment of alcoholism, on the level of consumption of ethanol solution and on activity of the microsomal monooxygenases of the liver in different stages of experimental alcoholism in rats.
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页码：1227 / 1229
页数：3
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