RECOGNITION OF SIZE AND CHARGED STATES OF ANTIGENS BY ANTIPEPTIDE ANTIBODIES

被引：3
|
作者：
SOHMA, Y [1 ]
ATSUSHI, M [1 ]
MORITA, H [1 ]
KATOH, S [1 ]
SADA, E [1 ]
机构：
[1] KYOTO UNIV,FAC ENGN,DEPT CHEM ENGN,SAKYO KU,KYOTO 606,JAPAN
来源：
JOURNAL OF FERMENTATION AND BIOENGINEERING | 1992年 / 73卷 / 06期
关键词：
D O I：
10.1016/0922-338X(92)90132-E
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The effects of the size and characteristics of peptide antigens on recognition and equilibrium between antigens and antibodies were studied by immunization of peptides with different characteristics. Four to five residues in the peptides were recognized by antibodies, and the charged states of the residues in the epitope strongly affected the immunointeraction. These results suggest a guideline for the selection of antigenic determinants to obtain antibodies suitable for immunoaffinity chromatography.
引用
收藏
页码：431 / 434
页数：4
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