FLUNARIZINE IN MIGRAINE PROPHYLAXIS - EFFICACY AND TOLERABILITY OF 5 MG AND 10 MG DOSE LEVELS

被引:20
|
作者
CENTONZE, V
MAGRONE, D
VINO, M
CAPORALETTI, P
ATTOLINI, E
CAMPANALE, G
ALBANO, O
机构
[1] Headache Unit, Department of Internal Medicine, University of Bari, Bari
关键词
Flunarizine; migraine prophylaxis; side effects;
D O I
10.1046/j.1468-2982.1990.1001017.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The use of flunarizine, a drug which has proven its efficacy in migraine, is often associated with important side effects. The aim of this paper has been to check their incidence at different dose levels (5 mg vs 10 mg). Our data confirm the occurrence of important side effects (in particular weight gain); on the other hand, they emphasize the dose-dependency of the side effects. © 1990, International Headache Society. All rights reserved.
引用
收藏
页码:17 / 24
页数:8
相关论文
共 50 条
  • [41] Prophylaxis of episodic Migraine: Rapid efficacy and good Tolerability of Fremanezumab
    Foerderreuther, Stefanie
    FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE, 2018, 86 (08) : 463 - +
  • [42] The efficacy and tolerability of anticonvulsants in the prophylaxis of migraine: an updated systematic review
    Chronicle, EP
    Mulleners, WM
    CEPHALALGIA, 2005, 25 (10) : 945 - 946
  • [43] Safety, tolerability, and efficacy of a fixed-dose combination of olmesartan 40 mg and hydrochlorothiazide 12.5/25 mg in daily practice
    Bramlage, Peter
    Zemmrich, Claudia
    Ketelhut, Reinhard
    Wolf, Wolf-Peter
    Fronk, Eva-Maria
    Schmieder, Roland E.
    VASCULAR HEALTH AND RISK MANAGEMENT, 2013, 9 : 475 - 483
  • [44] Efficacy of Rosuvastatin (5 mg and 10 mg) twice a week in patients intolerant to daily statins
    Gadarla, Mamatha
    Kearns, Amy K.
    Thompson, Paul D.
    AMERICAN JOURNAL OF CARDIOLOGY, 2008, 101 (12): : 1747 - 1748
  • [46] Sumatriptan 100 mg vs. 50 mg: pain-free efficacy and tolerability across 5 trials
    Richardson, M
    Winner, P
    Ames, M
    Lisk, L
    Jones, M
    CEPHALALGIA, 2003, 23 (07) : 704 - 704
  • [47] Sumatriptan in the acute treatment of migraine without aura: Efficacy of 50-mg dose
    Moschiano, F
    DAmico, D
    Grazzi, L
    Leone, M
    Bussone, G
    HEADACHE, 1997, 37 (07): : 421 - 423
  • [48] Zolmitriptan 2.5 mg orally disintegrating tablet for acute treatment of migraine: Part I, efficacy and tolerability
    Dowson, AJ
    Purdy, A
    MacGregor, EA
    NEUROLOGY, 2001, 56 (08) : A219 - A219
  • [49] A Randomized, One-Year Clinical Trial Comparing the Efficacy of Topiramate, Flunarizine, and a Combination of Flunarizine and Topiramate in Migraine Prophylaxis
    Luo, Ning
    Di, Wei
    Zhang, Aiwu
    Wang, Ying
    Ding, Minghui
    Qi, Weiwei
    Zhu, Yingting
    Massing, Mark W.
    Fang, Yannan
    PAIN MEDICINE, 2012, 13 (01) : 80 - 86
  • [50] Efficacy and Tolerability of Rizatriptan for the Treatment of Acute Migraine in Patients Taking Topiramate for Migraine Prophylaxis
    Seeburger, J. L.
    Cady, R. K.
    Winner, P.
    MacGregor, A.
    Valade, D.
    Ge, Y.
    Zhang, Y.
    Hustad, C.
    Strickler, N.
    Schaefer, E.
    Harper-Mozley, L.
    Fan, X.
    Hewitt, D.
    Ho, T.
    Connor, K. M.
    HEADACHE, 2010, 50 : S33 - S33