SUCCESSFUL USE OF HIGH-DOSE CYCLOPHOSPHAMIDE IN A CHILD WITH SEVERE AUTOIMMUNE HEMOLYTIC-ANEMIA

被引：0
|
作者：
PANCERI, R
FRASCHINI, D
TORNOTTI, G
MASERA, G
LOCASCIULLI, A
BACIGALUPO, A
机构：
[1] UNIV MILANO,DIV EMATOL PEDIAT,MONZA,ITALY
[2] OSPED SAN MARTINO GENOVA,DIPARTIMENTO EMATOL 2,GENOA,ITALY
来源：
HAEMATOLOGICA | 1992年 / 77卷 / 01期
关键词：
HIGH-DOSE CYCLOPHOSPHAMIDE; CHILDHOOD AUTOIMMUNE HEMOLYTIC ANEMIA;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report the case of a five-month-old boy with a life-threatening autoimmune hemolytic anemia that was unresponsive to conventional therapy with steroids, high-dose immunoglobulin, azathioprine and splenectomy. Despite these therapies, the patient's condition worsened, requiring 2-3 blood transfusions/day, since the hemoglobin level was constantly below 4 g/dl. We eventually increased immunosuppression by giving high-dose cyclophosphamide and the child showed a striking, sudden improvement, followed by complete recovery. No major long-term complications were observed.
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页码：76 / 78
页数：3
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