NEW MAJOR HISTOCOMPATIBILITY COMPLEX GENES

被引：47
|
作者：
MARSHALL, B
LEELAYUWAT, C
DEGLIESPOSTI, MA
PINELLI, M
ABRAHAM, LJ
DAWKINS, RL
机构：
[1] ROYAL PERTH HOSP,INST MOLEC GENET & IMMUNOL,DEPT CLIN IMMUNOL,PERTH,WA 6001,AUSTRALIA
[2] SIR CHARLES GAIRDNER HOSP,DEPT CLIN IMMUNOL,PERTH,WA,AUSTRALIA
[3] UNIV WESTERN AUSTRALIA,DEPT CLIN IMMUNOL,PERTH,WA,AUSTRALIA
来源：
HUMAN IMMUNOLOGY | 1993年 / 38卷 / 01期
关键词：
D O I：
10.1016/0198-8859(93)90516-4
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The MHC is a region of some 4 megabases that has been studied intensively owing to the large number of diseases chat are associated with susceptibility genes within this region of the genome. The total number of genes located within the MHC is now approximately 100, but more can be predicted. Recently identified genes within the MHC include PERB6, a large gene producing multiple transcripts located between HLA-B and TNF, and PERB1, a member of the protein tyrosine kinase-gene family. PERB6 was identified by YAC probing of tissue blots, while PERB1 was identified by genomic sequencing.
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页码：24 / 29
页数：6
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