AN EXPEDITIOUS SYNTHESIS OF SUBSTITUTED ISOXAZOLES FROM 6-ARYL-4-METHYLTHIO-2-OXO-2H-PYRAN-3-CARBONITRILES

被引：0
|
作者：
RAM, VJ
HUSSAINI, FA
SINGH, SK
SHOEB, A
机构：
来源：
JOURNAL OF CHEMICAL RESEARCH-S | 1993年 / 03期
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中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A one-step synthesis of substituted isoxazoles, 3-amino-6-arylpyrano[4,3-c]isoxazol-4-ones (2) and (3-arylisoxazol-5-yl)acetonitriles (4) by treating 6-aryl-4-methylthio-2-oxo-2H-pyran-3-carbonitriles with hydroxylamine hydrochloride is reported; the intermediacy of (3-aryl-5-methylthio-4,5-dihydroisoxazol-5-yl)acetonitriles (3) delineates the mechanism of the transformation of 1 into 4.
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页码：110 / 111
页数：2
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