THE DEVELOPMENT AND FUNCTION OF THE DROSOPHILA CNS MIDLINE CELLS

被引：31
|
作者：
NAMBU, JR [1 ]
LEWIS, JO [1 ]
CREWS, ST [1 ]
机构：
[1] UNIV CALIF LOS ANGELES, DEPT BIOL, INST MOLEC BIOL, LOS ANGELES, CA 90024 USA
来源：
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY | 1993年 / 104卷 / 03期
关键词：
D O I：
10.1016/0300-9629(93)90439-B
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
1. The midline cells of the Drosophila embryonic CNS comprise a discrete neuroanatomical structure consisting of a small subset of neurons and glia. 2. Developmental commitment of the CNS midline cells requires the action of dorsal/ventral patterning genes. 3. The single-minded gene encodes a basic-helix-loop-helix transcription factor and acts as a master regulator for the CNS midline lineage. 4. A number of different transcription factors and proteins involved in cell-cell interactions are necessary for the differentiation of midline neurons and glia. 5. CNS midline cells have important functions in the formation of the ventral epidermis and axon commissures.
引用
收藏
页码：399 / 409
页数：11
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