THE DEVELOPMENT AND FUNCTION OF THE DROSOPHILA CNS MIDLINE CELLS

被引：31
|
作者：
NAMBU, JR [1 ]
LEWIS, JO [1 ]
CREWS, ST [1 ]
机构：
[1] UNIV CALIF LOS ANGELES, DEPT BIOL, INST MOLEC BIOL, LOS ANGELES, CA 90024 USA
来源：
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY | 1993年 / 104卷 / 03期
关键词：
D O I：
10.1016/0300-9629(93)90439-B
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
1. The midline cells of the Drosophila embryonic CNS comprise a discrete neuroanatomical structure consisting of a small subset of neurons and glia. 2. Developmental commitment of the CNS midline cells requires the action of dorsal/ventral patterning genes. 3. The single-minded gene encodes a basic-helix-loop-helix transcription factor and acts as a master regulator for the CNS midline lineage. 4. A number of different transcription factors and proteins involved in cell-cell interactions are necessary for the differentiation of midline neurons and glia. 5. CNS midline cells have important functions in the formation of the ventral epidermis and axon commissures.
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收藏
页码：399 / 409
页数：11
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