EFFICIENT ONE-POT CONVERSION OF 6-METHYL-2-NITROANILINE INTO 1-ALKYLOXY-2-ALKYL-4-METHYL, 1-BENZYLOXY-2-PHENYL-4-METHYL, AND 1-ALLYLOXY-4-METHYL-2-VINYL-BENZIMIDAZOLE

被引：9
|
作者：
GARDINER, JM
LOYNS, CR
机构：
[1] Department of Chemistry, University of Manchester Institute of Science and Technology UMIST, Manchester M60 1QD
来源：
SYNTHETIC COMMUNICATIONS | 1995年 / 25卷 / 06期
关键词：
D O I：
10.1080/00397919508013418
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
6-Methyl-2-nitroaniline reacts with alkyl, benzyl and allyl halides and NaH as base, to afford 1-alkoxy-2-alkyl-, 1-benzyloxy-2-aryl- and 1-allyloxy-2-vinyl-benzimidazoles in good to excellent yields (73-98%), via a novel one-pot N-alkylation-heterocyclization-O-alkylation sequence.
引用
收藏
页码：819 / 827
页数：9
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