IMMUNE-MEDIATED MYELOPATHY AFTER ALLOGENEIC MARROW TRANSPLANTATION
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OPENSHAW, H
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CITY HOPE NATL MED CTR,DEPT HEMATOL & BONE MARROW TRANSPLANTAT,DUARTE,CA 91010CITY HOPE NATL MED CTR,DEPT HEMATOL & BONE MARROW TRANSPLANTAT,DUARTE,CA 91010
OPENSHAW, H
[1
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SLATKIN, NE
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CITY HOPE NATL MED CTR,DEPT HEMATOL & BONE MARROW TRANSPLANTAT,DUARTE,CA 91010CITY HOPE NATL MED CTR,DEPT HEMATOL & BONE MARROW TRANSPLANTAT,DUARTE,CA 91010
SLATKIN, NE
[1
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PARKER, PM
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CITY HOPE NATL MED CTR,DEPT HEMATOL & BONE MARROW TRANSPLANTAT,DUARTE,CA 91010CITY HOPE NATL MED CTR,DEPT HEMATOL & BONE MARROW TRANSPLANTAT,DUARTE,CA 91010
PARKER, PM
[1
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FORMAN, SJ
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CITY HOPE NATL MED CTR,DEPT HEMATOL & BONE MARROW TRANSPLANTAT,DUARTE,CA 91010CITY HOPE NATL MED CTR,DEPT HEMATOL & BONE MARROW TRANSPLANTAT,DUARTE,CA 91010
FORMAN, SJ
[1
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机构:
[1] CITY HOPE NATL MED CTR,DEPT HEMATOL & BONE MARROW TRANSPLANTAT,DUARTE,CA 91010
We describe two patients who developed myelopathy 15 and 27 months after allogeneic marrow transplantation. Exacerbations of the myelopathy occurred, with the development of optic neuropathy in one patient when corticosteroid therapy was tapered, The other patient had two exacerbations, 28 months and 40 months after transplantation, both of which resolved with plasmapheresis. These case reports suggest that immune-mediated disease after transplantation can affect the central nervous system.