ALU INSERTION POLYMORPHISM - A NEW TYPE OF MARKER FOR HUMAN-POPULATION STUDIES

被引：0
|
作者：
PERNA, NT
BATZER, MA
DEININGER, PL
STONEKING, M
机构：
[1] PENN STATE UNIV,DEPT ANTHROPOL,UNIV PK,PA 16802
[2] LOUISIANA STATE UNIV,MED CTR,DEPT BIOCHEM & MOLEC BIOL,NEW ORLEANS,LA 70112
[3] ALTON OCHSNER MED FDN & OCHSNER CLIN,MOLEC GENET LAB,NEW ORLEANS,LA 70121
来源：
HUMAN BIOLOGY | 1992年 / 64卷 / 05期
关键词：
ALU INTERSPERSED REPEATS; PCR; DNA POLYMORPHISM; GENETIC VARIATION;
D O I：
暂无
中图分类号：
Q98 [人类学];
学科分类号：
030303 ;
摘要：
A PCR-based method was used to screen 462 individuals from Japan, Papua New Guinea, Indonesia, and Australia for an Alu family insertion polymorphism. The frequency of this Alu insertion shows significant heterogeneity among island subgroups of the Indonesian sample and between the Japanese-Indonesian populations and the Australian-New Guinean populations. The simple, rapid PCR-based screening technique and the significant frequency differences among populations demonstrate that Alu insertion polymorphisms are potentially valuable markers for studies of the evolutionary history and migration patterns of modern humans.
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页码：641 / 648
页数：8
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