ANTI-CD40 ANTIBODY-BINDING MODULATES HUMAN MULTIPLE-MYELOMA CLONOGENICITY IN-VITRO

被引:0
|
作者
TONG, AW
SU, D
MUES, G
SOLANO, M
STONE, MJ
机构
[1] BAYLOR UNIV,BAYLOR SAMMONS CANC CTR,MED CTR,DALLAS,TX
[2] BAYLOR RES INST,M CROWLEY LAB,DALLAS,TX
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:A170 / A170
页数:1
相关论文
共 50 条
  • [41] Immunomodulatory drug lenalidomide (CC-5013, IMiD3) augments anti-CD40 SGN-40-induced cytotoxicity in human multiple myeloma: Clinical implications
    Tai, YT
    Li, XF
    Catley, L
    Coffey, R
    Breitkreutz, I
    Bae, J
    Song, WH
    Podar, K
    Hideshima, T
    Chauhan, D
    Schlossman, R
    Richardson, P
    Treon, SP
    Grewal, IS
    Munshi, NC
    Anderson, KC
    CANCER RESEARCH, 2005, 65 (24) : 11712 - 11720
  • [42] Extracellular matrix-binding form of anti-CD40 agonistic antibody reduces systemic damages and increases anti-tumor efficacy.
    Ishihara, A.
    Ishihara, J.
    Fukunaga, K.
    Hubbell, J. A.
    MOLECULAR BIOLOGY OF THE CELL, 2017, 28
  • [43] An Fc-Engineered Humanized Anti-CD40 Monoclonal Antibody, XmAb5485, Exhibits Potent Activity in Vitro and in Vivo against Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia and Multiple Myeloma
    Zhukovsky, Eugene A.
    Horton, Holly
    Peipp, Matthias
    Pong, Erik
    Bernett, Matthew
    Karki, Sher
    Richards, John
    Chu, Seung
    Repp, Roland
    Desjarlais, John
    BLOOD, 2008, 112 (11) : 325 - 326
  • [44] A novel human anti-CD40 monoclonal antibody, 4D11, for kidney transplantation in cynomolgus monkey.
    Imai, A
    Suzuki, T
    Sugitani, A
    Miura, T
    Itoh, T
    Todo, S
    AMERICAN JOURNAL OF TRANSPLANTATION, 2005, 5 : 292 - 292
  • [45] First-in-human clinical trial to assess pharmacokinetics, pharmacodynamics, safety, and tolerability of iscalimab, an anti-CD40 monoclonal antibody
    Espie, Pascal
    He, YanLing
    Koo, Phillip
    Sickert, Denise
    Dupuy, Cyrielle
    Chokote, Edwige
    Schuler, Roland
    Mergentaler, Heidi
    Ristov, Jacinda
    Milojevic, Julie
    Verles, Aurelie
    Groenewegen, Andrea
    Auger, Anita
    Avrameas, Alexandre
    Rotte, Michael
    Colin, Laurence
    Tomek, Charles S.
    Hernandez-Illas, Martha
    Rush, James S.
    Gergely, Peter
    AMERICAN JOURNAL OF TRANSPLANTATION, 2020, 20 (02) : 463 - 473
  • [46] Novel fully human Anti-CD40 monoclonal antibody, 4D11, for kidney transplantation in cynomolgus monkeys
    Imai, Atsushi
    Suzuki, Tomomi
    Sugitani, Atsushi
    Itoh, Tomoo
    Ueki, Shinya
    Aoyagi, Takeshi
    Yamashita, Kenichiro
    Taniguchi, Masahiko
    Takahashi, Nobuaki
    Miura, Toru
    Shimamura, Tsuyoshi
    Furukawa, Hiroyuki
    Todo, Satoru
    TRANSPLANTATION, 2007, 84 (08) : 1020 - 1028
  • [47] Pharmacokinetics and Pharmacodynamics of ASKP1240, a Fully Human Anti-CD40 Antibody, in Normal and Renal Transplanted Cynomolgus Monkeys
    Ma, Anlun
    Dun, Hao
    Song, Lijun
    Hu, Yanxin
    Zeng, Lin
    Bai, Jieying
    Zhang, Guangzhou
    Kinugasa, Fumitaka
    Miyao, Yasuhiro
    Sakuma, Shozo
    Okimura, Kazumichi
    Kasai, Noriyuki
    Daloze, Pierre
    Chen, Huifang
    TRANSPLANTATION, 2014, 97 (04) : 397 - 404
  • [48] Proapoptotic signaling activity of the anti-CD40 monoclonal antibody dacetuzumab circumvents multiple oncogenic transformation events and chemosensitizes NHL cells
    T S Lewis
    R S McCormick
    I J Stone
    K Emmerton
    B Mbow
    J Miyamoto
    J G Drachman
    I S Grewal
    C-L Law
    Leukemia, 2011, 25 : 1007 - 1016
  • [49] Immunomodulatory drug lenalidomide (CC-5013, IMiD3) augments anti-CD40 SGN-40-induced cytotoxicity in human multiple myeloma: Clinical implications.
    Tai, YT
    Catley, L
    Li, XF
    Coffey, R
    Breitkreutz, I
    Bae, J
    Podar, K
    Hideshima, T
    Chauhan, D
    Schlossman, R
    Richardson, P
    Treon, SP
    Grewal, IS
    Munshi, NC
    Anderson, KC
    BLOOD, 2005, 106 (11) : 370B - 370B
  • [50] Proapoptotic signaling activity of the anti-CD40 monoclonal antibody dacetuzumab circumvents multiple oncogenic transformation events and chemosensitizes NHL cells
    Lewis, T. S.
    McCormick, R. S.
    Stone, I. J.
    Emmerton, K.
    Mbow, B.
    Miyamoto, J.
    Drachman, J. G.
    Grewal, I. S.
    Law, C-L
    LEUKEMIA, 2011, 25 (06) : 1007 - 1016