TOTAL SYNTHESIS OF (-)-BALANOL

被引：96
|
作者：
LAMPE, JW
HUGHES, PF
BIGGERS, CK
SMITH, SH
HU, H
机构：
[1] Department of Chemical Research, Sphinx Pharmaceuticals Corporation, Durham, North Carolina 27717, Four University Place
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 18期
关键词：
D O I：
10.1021/jo00097a014
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
(-)-Balanol, a fungal metabolite with potent protein kinase C inhibitory properties, has been prepared in a total synthesis which makes use of an anionic homo-Fries rearrangement approach to the benzophenone subunit and in which the azepane subunit is obtained from (2S,3R)-3-hydroxylysine.
引用
收藏
页码：5147 / 5148
页数：2
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