ULTRASTRUCTURAL-STUDY OF NEUROMUSCULAR-JUNCTION IN RECTUS FEMORIS MUSCLE OF STREPTOZOTOCIN-DIABETIC RATS

被引：0
|
作者：
SANCHEZ, MM
SANCHEZ, CR
ALVAREZ, JAV
PELAEZ, AM
机构：
[1] UNIV OVIEDO,DEPT SURG,OVIEDO,SPAIN
[2] UNIV OVIEDO,DEPT MORPHOL SCI & CELL BIOL,OVIEDO,SPAIN
来源：
HISTOLOGY AND HISTOPATHOLOGY | 1992年 / 7卷 / 04期
关键词：
QUADRICEPS MUSCLE; RAT; STREPTOZOTOCIN DIABETES; ULTRASTRUCTURE; NEUROMUSCULAR JUNCTION;
D O I：
暂无
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The neuromuscular junctions (NMJ) from rectus femoris muscle in streptozotocin (STZ) -induced diabetic rats were examined by electron microscopy eight weeks after the STZ injection. When compared to controls and vehicle-injected groups, both the axon terminal and the junctional sarcoplasm showed serious alterations including mitochondrial degeneration, presence of myeloid bodies, breakdown of presynaptic membrane and changes in the form of the synaptic vesicles. The results suggest that NMJ can contribute to the pathogenesis of diabetic proximal myopathy.
引用
收藏
页码：607 / 610
页数：4
相关论文
共 50 条
  • [31] CONTRACTILE AND RELAXING ACTIVITY OF ARTERIAL SMOOTH-MUSCLE FROM STREPTOZOTOCIN-DIABETIC RATS
    PFAFFMAN, MA
    HILMAN, R
    DARBY, A
    RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY, 1980, 30 (02): : 283 - 299
  • [32] Cerebral metabolism in streptozotocin-diabetic rats: an in vivo magnetic resonance spectroscopy study
    Biessels, GJ
    Braun, KPJ
    de Graaf, RA
    van Eijsden, P
    Gispen, WH
    Nicolay, K
    DIABETOLOGIA, 2001, 44 (03) : 346 - 353
  • [33] END-STAGE FIBROSIS OF THE LATERAL RECTUS MUSCLE IN MYOPIA WITH ESOTROPIA - AN ULTRASTRUCTURAL-STUDY
    MEYER, E
    LUDATSCHER, RM
    LICHTIG, C
    SHAULY, Y
    GDALON, M
    OPHTHALMIC RESEARCH, 1990, 22 (04) : 259 - 264
  • [34] Correlative morphometric and biochemical study on pancreatic amylase in normal and streptozotocin-diabetic rats
    Aughsteen, AA
    Kataoka, K
    Shair, SA
    PANCREAS, 1996, 13 (03) : 295 - 303
  • [35] MINERALIZATION OF DIFFERENT BONES IN STREPTOZOTOCIN-DIABETIC RATS - STUDY ON THE CONCENTRATION OF 8 MINERALS
    ROSHOLT, MN
    HEGARTY, PVJ
    AMERICAN JOURNAL OF CLINICAL NUTRITION, 1981, 34 (09): : 1680 - 1685
  • [36] Cerebral metabolism in streptozotocin-diabetic rats: an in vivo magnetic resonance spectroscopy study
    G. J. Biessels
    K. P. J. Braun
    R. A. de Graaf
    P. van Eijsden
    W. H. Gispen
    K. Nicolay
    Diabetologia, 2001, 44 : 346 - 353
  • [37] Impaired paracrine effect of endothelin-1 on vascular smooth muscle in streptozotocin-diabetic rats
    Wu, SQ
    Tang, F
    CARDIOVASCULAR RESEARCH, 1998, 39 (03) : 651 - 656
  • [38] Phenotype modulation in primary cultures of aortic smooth muscle cells from streptozotocin-diabetic rats
    Etienne, P
    Parés-Herbuté, N
    Mani-Ponset, L
    Gabrion, J
    Rabesandratana, H
    Herbuté, S
    Monnier, L
    DIFFERENTIATION, 1998, 63 (04) : 225 - 236
  • [39] Regulation of SIRT1 in Vascular Smooth Muscle Cells from Streptozotocin-Diabetic Rats
    Toniolo, Alice
    Warden, Erica Alessia
    Nassi, Alberto
    Cignarella, Andrea
    Bolego, Chiara
    PLOS ONE, 2013, 8 (05):
  • [40] Ultrastructural study on the photoreceptor layer in streptozotocin-induced diabetic rats
    Goodarzi A.
    Esfandiari A.
    Dehghansheibani A.
    Comparative Clinical Pathology, 2014, 23 (5) : 1293 - 1297
12345