POSITRON EMISSION TOMOGRAPHY-EVALUATION OF DOPAMINERGIC PATHWAYS

被引：0
|
作者：
PERLMUTTER, JS [1 ]
机构：
[1] WASHINGTON UNIV,SCH MED,DEPT NEUROL & NEUROL SURG NEUROL,ST LOUIS,MO
来源：
CLINICAL NEUROPHARMACOLOGY | 1995年 / 18卷
关键词：
POSITRON EMISSION TOMOGRAPHY; DOPAMINE; PARKINSONS DISEASE; RECEPTORS; TRANSMITTERS;
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Positron emission tomography (PET) studies of dopamine receptors have provided exciting new insights into basal ganglia function that are particularly relevant to Parkinson's disease. Previous studies have concentrated on alterations in radioligand binding of primarily D-2-like dopaminergic binding sites. Development of new radioligands with greater dopamine subtype specificity promises to reveal additional information about dopaminergic function. Also, pharmacological activation techniques with PET may permit identification of alterations in receptor-mediated pathways not associated with direct changes in receptors.
引用
收藏
页码：S188 / S194
页数：7
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