Antituberculosis Activity of Natural and Synthetic Compounds

被引:0
|
作者
Rogoza, L. N. [1 ]
Salakhutdinov, N. F. [1 ]
Tolstikov, G. A. [1 ]
机构
[1] Russian Acad Sci, Siberian Branch, Vorozhtsov Novosibirsk Inst Organ Chem, Prospekt Akademika Lavrentyeva 9, Novosibirsk 630090, Russia
来源
CHEMISTRY FOR SUSTAINABLE DEVELOPMENT | 2010年 / 18卷 / 04期
关键词
tuberculosis; tuberculosis with plural drug resistance; M; antimycobacterial activity; antituberculosis activity; cytotoxicity; structure-property relationship;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The review presents the most active natural and synthetic compounds those exhibit antimycobacterial activity providing the minimum inhibiting concentration (MIC) <= 5 mu g/mL. For better understanding the structure-activity relationship, compounds with a high value of MIC are considered in some cases. The review covers the papers published within the range of 2001-first half of 2009. The information in the review is systematized with respect to chemical structures (the nitrogen-, oxygen-, sulphur-containing heterocyclic compounds, peptides, alkaloids, terpenoids and others.).
引用
收藏
页码:343 / 375
页数:33
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