PLOIDY IN BONE-MARROW CELLS FROM HEALTHY DONORS - A MAC (MORPHOLOGY ANTIBODY CHROMOSOMES) STUDY

被引：8
|
作者：
LARRAMENDY, ML
NYLUND, SJ
WESSMAN, M
RUUTU, T
KNUUTILA, S
机构：
[1] UNIV HELSINKI,DEPT MED GENET,SF-00014 HELSINKI,FINLAND
[2] UNIV NACL LA PLATA,FAC CIENCIAS NAT,CITOGENET LAB,LA PLATA,BUENOS AIRES,ARGENTINA
[3] UNIV NACL LA PLATA,MUSEO LA PLATA,CITOGENET LAB,LA PLATA,BUENOS AIRES,ARGENTINA
[4] UNIV NACL LA PLATA,FAC CIENCIAS AGR & FORESTALES,LA PLATA,BUENOS AIRES,ARGENTINA
[5] UNIV HELSINKI,CENT HOSP,DEPT MED 3,SF-00290 HELSINKI,FINLAND
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 1994年 / 86卷 / 01期
关键词：
PLOIDY; BONE MARROW CELLS; MORPHOLOGY ANTIBODY CHROMOSOMES TECHNIQUE;
D O I：
10.1111/j.1365-2141.1994.tb03279.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The ploidy of human bone marrow cells belonging to the megakaryocytic, granulocytic-monocytic and erythrocytic lineages was studied by in situ hybridization using the biotin-labelled Y chromosome-specific DNA probe pY431 and the chromosome 1-specific probe pUC1.77 on cells identified morphologically and immunologically by the MAC procedure. Cells of the granulocytic-monocytic and erythrocytic lineages were seen to be 2N in ploidy, whereas the ploidy of the megakaryocytic lineage ranged from 2N to 32N, with the ploidy classes 4N and 8N being predominant. The frequency of megakaryocytes with 2N chromosomes was also high.
引用
收藏
页码：203 / 206
页数：4
相关论文
共 50 条
  • [41] BURSAL ORIGIN OF BONE-MARROW CELLS WITH COMPETENCE FOR ANTIBODY-FORMATION
    IVANYI, J
    LYDYARD, PM
    MURGATROYD, LB
    IMMUNOLOGY, 1972, 23 (01) : 107 - +
  • [42] EFFECT OF STIMULATION OF ANTIBODY-FORMATION BY BONE-MARROW CELLS INVIVO
    SERGEEV, YO
    MIKHAILOVA, AA
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1978, 85 (04) : 487 - 489
  • [43] STUDIES ON THE BONE-MARROW CELLS FROM AN EXCISED PIPE BONE
    TAKAKUWA, K
    KURATA, H
    HIRONO, T
    KOIKE, T
    KISHI, K
    SHIBATA, A
    TANAKA, K
    HEMATOLOGIC PATHOLOGY, 1993, 7 (02) : 107 - 118
  • [44] THE PROLIFERATIVE ACTIVITY OF ANTIBODY-FORMING-CELLS IN THE MOUSE BONE-MARROW
    KOCH, G
    LOK, BD
    BENNER, R
    ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, 1982, 149 : 75 - 81
  • [45] DEPLETION OF BREAST-CANCER CELLS FROM AUTOLOGOUS BONE-MARROW IN PREPARATION FOR BONE-MARROW TRANSPLANTATION
    MORECKI, S
    MARGEL, S
    SLAVIN, S
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1988, 29 : 183 - 183
  • [46] ELIMINATION OF LEUKEMIC-CELLS FROM RAT BONE-MARROW USING ANTIBODY AND COMPLEMENT (C')
    BAST, RC
    FEENEY, M
    GREENBERGER, JS
    KNAPP, RC
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1979, 20 (MAR): : 239 - 239
  • [47] DISTRIBUTION OF A MONOCLONAL-ANTIBODY RAISED AGAINST RETICULAR CELLS FROM MURINE BONE-MARROW
    DEJONG, JP
    WILLEMSEN, R
    PIERSMA, AH
    NIKKELS, PGJ
    VOERMAN, JSA
    PLOEMACHER, RE
    EXPERIMENTAL HEMATOLOGY, 1986, 14 (06) : 495 - 495
  • [48] Assessment of dysplastic hematopoiesis: lessons from healthy bone marrow donors
    Parmentier, Stefani
    Schetelig, Johannes
    Lorenz, Kerstin
    Kramer, Michael
    Ireland, Robin
    Schuler, Ulrich
    Ordemann, Rainer
    Rall, Gabi
    Schaich, Markus
    Bornhaeuser, Martin
    Ehninger, Gerhard
    Kroschinsky, Frank
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2012, 97 (05): : 723 - 730
  • [49] STUDY OF EFFECT OF ALCOHOL ON BLOOD AND BONE-MARROW CELLS
    MATHESON, J
    CANADIAN JOURNAL OF MEDICAL TECHNOLOGY, 1974, 36 (06): : 493 - 501
  • [50] STUDY OF EFFECT OF ALCOHOL ON BLOOD AND BONE-MARROW CELLS
    MATHESON, J
    CANADIAN JOURNAL OF MEDICAL TECHNOLOGY, 1974, 36 (05): : 415 - 415
12345