TREATMENT OF ADVANCED BREAST-CANCER WITH 20 MG TOREMIFENE, A PHASE-II STUDY - PRELIMINARY COMMUNICATION

被引：8
|
作者：
PYRHONEN, S
VALAVAARA, R
HEIKKINEN, M
RISSANEN, P
BLANCO, G
NORDMAN, E
HOLSTI, LR
HAJBA, A
机构：
[1] FARMOS GRP LTD,RES CTR,TURKU,FINLAND
[2] UNIV TURKU,CENT HOSP,DEPT RADIOTHERAPY & ONCOL,SF-20500 TURKU 50,FINLAND
[3] UNIV OULU,CENT HOSP,SF-90220 OULU 22,FINLAND
来源：
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY | 1990年 / 36卷 / 03期
关键词：
D O I：
10.1016/0022-4731(90)90011-G
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Fourteen postmenopausal women with estrogen-receptor positive advanced breast cancer and no prior cytostatic treatment received 20 mg toremifene daily as a single dose after a loading dose (120→60→60 mg) for the first 3 days. All were evaluable and had undergone at least 6 weeks' treatment. Results were: no complete remissions (CR), 3 partial remissions (PR), 8 no change (NC) and 3 cases of progressive disease (PD). Three patients had mild side effects: nausea, insomnia, sweating and arm pain. © 1990.
引用
收藏
页码：227 / 228
页数：2
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