Noninvasive prenatal fetal genotyping from cell-free maternal plasma

被引:0
|
作者
Dauber, E. M. [1 ]
Mayr, W. R. [1 ]
机构
[1] Med Univ Vienna, Dept Blood Grp Serol & Transfus Med, Vienna, Austria
关键词
Prenatal genotyping; Cell-free DNA; Indel-polymorphism; Mini-STR;
D O I
10.1016/j.fsigss.2013.10.116
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Fetal cell-free DNA circulating in maternal plasma is a possible target for various prenatal investigations of the unborn child. Typing of autosomal and gonosomal short tandem repeat and insertion-deletion polymorphisms was carried out in two pregnancies. Competitive PCR was tested versus allele and haplotype specific PCR by conventional and real-time PCR techniques. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:E226 / E227
页数:2
相关论文
共 50 条
  • [41] Noninvasive fetal RHD genotyping from maternal plasma in an admixed Brazilian population
    Schmidt, L. C.
    Cabral, A. C. V.
    Faria, M. A.
    Monken, F.
    Tarazona-Santos, E.
    Martins, M. L.
    GENETICS AND MOLECULAR RESEARCH, 2014, 13 (01) : 799 - 805
  • [42] Prenatal diagnosis of homozygous alpha-thalassemia-1 by cell-free fetal DNA in maternal plasma
    Sirichotiyakul, S.
    Charoenkwan, P.
    Sanguansermsri, T.
    PRENATAL DIAGNOSIS, 2012, 32 (01) : 45 - 49
  • [43] CIRCULATING CELL-FREE FETAL DNA IN MATERNAL PLASMA: PROSPECTS FOR NON-INVASIVE PRENATAL ASSESSMENT OF FETAL ANEUPLOIDIES
    van den Boom, D.
    Ehrich, M.
    Deciu, C.
    Bombard, A.
    CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2011, 49 : S92 - S92
  • [44] Early detection of cell-free fetal DNA in maternal plasma
    Illanes, S.
    Denbow, M.
    Kailasam, C.
    Finning, K.
    Soothill, P. W.
    EARLY HUMAN DEVELOPMENT, 2007, 83 (09) : 563 - 566
  • [45] Both maternal and fetal cell-free DNA in plasma fluctuate
    Hahn, SU
    Zhong, UY
    Bürk, MR
    Troeger, C
    Kang, AJ
    Holzgreve, W
    CIRCULATING NUCLEIC ACIDS IN PLASMA OR SERUM II, 2001, 945 : 141 - 144
  • [46] Noninvasive fetal RHD genotyping by maternal plasma with capillary electrophoresis
    Kimura, Machiko
    Sato, Chiaki
    Hara, Masaaki
    Ishihara, Osamu
    Ikebuchi, Kenji
    TRANSFUSION, 2008, 48 (06) : 1156 - 1163
  • [47] Posttest risk calculation following positive noninvasive prenatal screening using cell-free DNA in maternal plasma
    Benn, Peter
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2016, 214 (06) : 676.e1 - 676.e7
  • [48] Kinetics of fetal cellular and cell-free DNA in the maternal circulation during and after pregnancy: implications for noninvasive prenatal diagnosis
    Ariga, H
    Ohto, H
    Busch, MP
    Imamura, S
    Watson, R
    Reed, W
    Lee, TH
    TRANSFUSION, 2001, 41 (12) : 1524 - 1530
  • [49] Prenatal genotyping of fetal RHD in maternal plasma from RHD negative women
    Stamna, A.
    Zoumatzi, B.
    Manitsa, A.
    Vavatsi-Christaki, N.
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2007, 92 : 398 - 398
  • [50] Fetal cell-free DNA fraction in maternal plasma is affected by fetal trisomy
    Nobuhiro Suzumori
    Takeshi Ebara
    Takahiro Yamada
    Osamu Samura
    Junko Yotsumoto
    Miyuki Nishiyama
    Kiyonori Miura
    Hideaki Sawai
    Jun Murotsuki
    Michihiro Kitagawa
    Yoshimasa Kamei
    Hideaki Masuzaki
    Fumiki Hirahara
    Juan-Sebastian Saldivar
    Nilesh Dharajiya
    Haruhiko Sago
    Akihiko Sekizawa
    Journal of Human Genetics, 2016, 61 : 647 - 652