THE EPIDEMIOLOGY OF NEURAL-TUBE DEFECTS - A MATHEMATICAL-MODEL

被引：8
|
作者：
VANROOTSELAAR, FJ
机构：
[1] 7573 BV Oldenzaal
来源：
MEDICAL HYPOTHESES | 1993年 / 41卷 / 01期
关键词：
D O I：
10.1016/0306-9877(93)90039-S
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The incidence of neural tube defects (NTDs) shows a seasonal variation; and incidence as well as female/male ratio show a relation with latitude. The interrelation of these phenomena is presented as a mathematical model, which has a 'predictive' value, and is an instrument in estimating the local gene frequency. The model offer's a simple explanation of the conundrum why the double X-chromosome has a variable influence on the sex ratio. UV light and the herpes virus fit in this model as related causative factors of NTDs.
引用
收藏
页码：78 / 82
页数：5
相关论文
共 50 条
  • [31] PREVENTING NEURAL-TUBE DEFECTS
    OBRIEN, GJ
    MEDICAL JOURNAL OF AUSTRALIA, 1981, 1 (13) : 718 - 718
  • [32] NEURAL-TUBE DEFECTS AND TWINNING
    LECK, I
    LANCET, 1974, 1 (7849): : 178 - 178
  • [33] VITAMINS AND NEURAL-TUBE DEFECTS
    HARRIS, R
    BRITISH MEDICAL JOURNAL, 1988, 296 (6615): : 80 - 81
  • [34] NEURAL-TUBE DEFECTS - INTRODUCTION
    HALL, JG
    NEURAL TUBE EFFECTS, 1994, 181 : 1 - 3
  • [35] PREVENTION OF NEURAL-TUBE DEFECTS
    SUTCLIFFE, M
    WILD, J
    PERRY, A
    SCHORAH, CJ
    LANCET, 1994, 344 (8936): : 1578 - 1578
  • [36] POTATOES AND NEURAL-TUBE DEFECTS
    RENWICK, JH
    LANCET, 1973, 2 (7828): : 562 - 562
  • [37] SCREENING FOR NEURAL-TUBE DEFECTS
    BRERETON, RJ
    CUDMORE, RE
    IRVING, IM
    LISTER, J
    BUYUKPANUKCU, N
    LANCET, 1978, 1 (8069): : 879 - 879
  • [38] PREVENTION OF NEURAL-TUBE DEFECTS
    HOLMES, LB
    JOURNAL OF PEDIATRICS, 1992, 120 (06): : 918 - 919
  • [39] SCREENING FOR NEURAL-TUBE DEFECTS
    CUCKLE, HS
    NEURAL TUBE EFFECTS, 1994, 181 : 253 - 266
  • [40] SCREENING FOR NEURAL-TUBE DEFECTS
    DUNN, PM
    LANCET, 1980, 1 (8168): : 600 - 600
12345