SCIENTIFIC EVALUATION OF THE SAFETY FACTOR FOR THE ACCEPTABLE DAILY INTAKE (ADI) - CASE-STUDY - BUTYLATED HYDROXYANISOLE (BHA)

被引：0
|
作者：
WURTZEN, G
机构：
来源：
FOOD ADDITIVES AND CONTAMINANTS | 1993年 / 10卷 / 03期
关键词：
ACCEPTABLE DAILY INTAKE; ADI; SAFETY FACTORS; FOOD ADDITIVES; BUTYLATED HYDROXYANISOLE; BHA;
D O I：
暂无
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The principles of 'data-derived safety factors' are applied to toxicological and biochemical information on butylated hydroxyanisole (BHA). The calculated safety factor for an ADI is, by this method, comparable to the existing internationally recognized safety evaluations. Relevance for humans of forestomach tumours in rodents is discussed. The method provides a basis for organizing data in a way that permits an explicit assessment of its relevance.
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页码：307 / 314
页数：8
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