Two groups of cells, one rounded or oval and the other spindle-shaped, were found in a case of plexiform fibrohistiocytic tumor. Immunohistochemistry was strongly positive for alpha smooth muscle actin in most cells of both types but stronger in the spindle-shaped cells, suggesting a myofibroblastic origin. This was in correlation with electron microscopic findings which revealed fibroblasts, myofibroblasts and some undifferentiated mesenchymal cells. However, factor XIIIa was negative suggesting that this tumor does not originate from dermal dendrocytes.
机构:
Mem Sloan Kettering Canc Ctr, Dept Radiol, 1275 York Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiol, 1275 York Ave, New York, NY 10065 USA
Ghuman, Marcus
Hwang, Sinchun
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机构:
Mem Sloan Kettering Canc Ctr, Dept Radiol, 1275 York Ave, New York, NY 10065 USA
Cornell Univ, Weill Med Coll, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiol, 1275 York Ave, New York, NY 10065 USA
Hwang, Sinchun
Antonescu, Cristina R.
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Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiol, 1275 York Ave, New York, NY 10065 USA
Antonescu, Cristina R.
Panicek, David M.
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Mem Sloan Kettering Canc Ctr, Dept Radiol, 1275 York Ave, New York, NY 10065 USA
Cornell Univ, Weill Med Coll, New York, NY 10065 USAMem Sloan Kettering Canc Ctr, Dept Radiol, 1275 York Ave, New York, NY 10065 USA