Aggregational Activity Of Thrombocytes In Patients With Type 2 Diabetes Mellitus

High pathological burden of modern society is largely associated with the prevalence among the general population of the world of type 2 diabetes. The special danger of this disease is associated with the frequent development of thromboses caused by hyperaggregation of blood cells, the nature of which has not been studied sufficiently. The goal is to assess the level of platelet aggregation in type 2 diabetes mellitus. We examined 36 patients of the second adulthood (mean age 47.4 +/- 2.1 years) with type 2 diabetes mellitus. The control group consisted of 26 clinically healthy people of the same age. All examined persons gave written informed consent to participate in the study. Biochemical, hematological and statistical methods of investigation were used. The frequency of high thrombosis of various localizations in type 2 diabetes is closely related to the development of angiopathy against their background. Weakening of antioxidant protection of plasma with activation of processes of lipid peroxidation in it, leading to a change in the vascular wall, is noted in conditions of type 2 diabetes mellitus. It was found that people with type 2 diabetes mellitus have an obvious weakening of disaggregation of vascular wall vascular impacts with increasing platelet aggregation capacity. As a result, patients receive a sharply increased risk of thrombosis of any location, which can lead to disability and death.