Discoid Lupus Erythematosus in Childhood: A Report of Two Cases and Review of the Literature

Discoid lupus erythematosus (DLE) is an uncommon disease in childhood. The lesions are similar to adults, are seen more frequently on sun-exposed areas. Discoid skin lesions, characterized by scaly, erythematous, telangiectatic papules and plaques. Histopathological and immunohistochemical studies are similar to that of adult patients. Antinuclear antibody (ANA) positivity can be seen in laboratory investigations. Topical agents such as topical steroids and topical calcineurin inhibitors can be used with sun protection for the treatment. We report two pediatric patients who presented to our out-patient clinic with persistent wound on the face. One of them had symetrical atrophic plaques on the lower eyelids, the other had an erythematous plaque on the right lower eyelid. Skin biopsy samples was performed from the lesions of two patients. Laboratory examinations were within normal limits. The patients were diagnosed as DLE and outpatient follow-up was recommended. Although the incidence of DLE is uncommon in childhood, the risk of development systemic lupus erythematosus is more frequently reported compared to adult patients. Therefore, inorder to check for the ANA titers and other clinical and laboratory parameters regular follow-up of pediatric patients is essential.