SYSTEMIC HISTIOCYTOSIS PRESENTING AS MULTIPLE-SCLEROSIS

被引:25
|
作者
SMITH, ME
KATZ, DA
HARRIS, JO
FRANK, JA
KUFTA, CV
MCFARLIN, DE
机构
[1] NINCDS,SURG NEUROL BRANCH,BETHESDA,MD 20892
[2] NINCDS,OFF CLID DIRECTOR,BETHESDA,MD 20892
[3] NCI,PATHOL LAB,BETHESDA,MD 20892
[4] NIH,DIAGNOST REDIOL RES PROGRAM,BETHESDA,MD 20892
关键词
D O I
10.1002/ana.410330521
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A patient resembling one with Progressive multiple sclerosis in clinical presentation and by magnetic resonance imaging was studied in detail. Some features atypical for multiple sclerosis prompted a persistent search for an alternative cause. The diagnosis of a non-Langerhans systemic histiocytosis involving brain and bone was established and showed a partial response to radiation therapy. This patient illustrates the continued importance of a broad approach to the evaluation of possible multiple sclerosis, with particular attention to atypical features.
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页码:549 / 554
页数:6
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