Novel synthesis, characterization and antimicrobial activity of some new 3, 5-diarylpyrazolines

被引:0
|
作者
Bhise, M. P. [1 ]
Raut, V. M. [1 ]
Pawar, R. P. [1 ]
Gulwade, G. P. [1 ]
Junghare, N. A. [2 ]
Murhekar, G. H. [1 ]
机构
[1] Govt Vidarbha Inst Sci & Humanities, Dept Chem, Amravati, India
[2] MCTs Rajiv Gandhi Inst Technol, Andheri W Mumbai, India
关键词
3-(2-Hydroxyphenyl)-4-aroyl-5-arylpyrazoline; Antimicrobial activity;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
3-Aroyl flavanones were allowed to react with hydrazine hydrate in dioxane containing little piperidine to give corresponding 3-(2-hydroxyphenyl)-4-aroyl-5-arylpyrazolines. Their structural assignment are based on elemental analysis, spectral data (IR, UV & NMR) and chemical properties. All these compounds were tested in vitro for their antibacterial activity by disk-diffusion method against gram positive and gram negative bacterias. In some of the compounds the results are found to be encouraging.
引用
收藏
页码:1065 / 1069
页数:5
相关论文
共 50 条
  • [21] Synthesis, characterization and in vitro antimicrobial activity of some new Schiff bases and their complexes
    Hossein Naeimi
    Zahra Sadat Nazifi
    Seyedeh Matin Amininezhad
    Mehdi Amouheidari
    The Journal of Antibiotics, 2013, 66 : 687 - 689
  • [22] Synthesis, Characterization, and Antimicrobial Activity of Some New Tetrazole Derivatives from Hydrazones
    Sajjad, Ahmed
    Al Shuhaib, Zainab
    IRANIAN JOURNAL OF CHEMISTRY & CHEMICAL ENGINEERING-INTERNATIONAL ENGLISH EDITION, 2022, 41 (07): : 2247 - 2262
  • [23] Synthesis, spectral characterization and in vitro antimicrobial activity of some new azopyridine derivatives
    Abuo-Melha, Hanaa
    Fadda, A. A.
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2012, 89 : 123 - 128
  • [24] Synthesis of some new pyrazoles and their antimicrobial activity
    Gajare, AS
    Bhawsar, SB
    Shingare, MS
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 1997, 6 (04) : 321 - 322
  • [25] Synthesis and antimicrobial activity of some new isoxazoles
    Nagar, DN
    Mehta, T
    Shah, VH
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2003, 13 (02) : 173 - 174
  • [26] Synthesis and antimicrobial activity of some new α-aminophosphonates
    Srinivasulu, Kambam
    Raju, C. Naga
    Babu, Y. Hari
    Reddy, A. Lava Kumar
    SOUTH AFRICAN JOURNAL OF CHEMISTRY-SUID-AFRIKAANSE TYDSKRIF VIR CHEMIE, 2007, 60 : 47 - 51
  • [27] Synthesis and antimicrobial activity of some new sulphonamidofluorobenzothiazoles
    Kumar, Jitender
    Ghate, Manjunath
    Pal, Palash
    Baidya, Mayukh
    Das, Amit Kumar
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2007, 17 (02) : 199 - 200
  • [28] Synthesis, characterization and in vitro antimicrobial activity of some novel 5-substituted Schiff and Mannich base of isatin derivatives
    Prakash, Chinnasamy Rajaram
    Raja, Sundararajan
    JOURNAL OF SAUDI CHEMICAL SOCIETY, 2013, 17 (03) : 337 - 344
  • [29] Synthesis, Characterization and Antimicrobial Activity of Some Novel 1-substituted Benzimidazole Derivatives
    Isik, Erkut
    Astley, Demet
    Yuksekdanaci, Seda
    Yasa, Ihsan
    LETTERS IN DRUG DESIGN & DISCOVERY, 2020, 17 (11) : 1372 - 1379
  • [30] Synthesis, characterization and antimicrobial activity of some novel 1-amino dibenzofuran derivatives
    Shafi, S. Syed
    Subaash, R.
    Senthilkumar, S.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2021, 60 (07): : 1022 - 1026