Based on morphological, virological, biochemical and molecular biological data, it is proposed that the presence of endogenous retrovirus particles in the placental cytotrophoblasts of many mammals is indicative of some beneficial action provided by the virus in relation to cell fusion. syncytiotrophoblast formation and the creation of the placenta. Further, it is hypothesised that the germ line retroviral infection of some primitive mammal-like species resulted in the evolution of the placental mammals.
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UCL, Dept Genet Evolut & Environm, Gower St, London WC1E 6BT, England
Univ Birmingham, Sch Geog Earth & Environm Sci, Edgbaston B15 2TT, EnglandUCL, Dept Genet Evolut & Environm, Gower St, London WC1E 6BT, England
Halliday, Thomas J. D.
dos Reis, Mario
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Queen Mary Univ London, Sch Biol & Chem Sci, Mile End Rd, London E1 4NS, EnglandUCL, Dept Genet Evolut & Environm, Gower St, London WC1E 6BT, England
dos Reis, Mario
Tamuri, Asif U.
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UCL, Res IT Serv, Gower St, London WC1E 6BT, England
Wellcome Genome Campus, European Bioinformat, European Mol Biol Lab, Hinxton CB10 1SD, Cambs, EnglandUCL, Dept Genet Evolut & Environm, Gower St, London WC1E 6BT, England
Tamuri, Asif U.
Ferguson-Gow, Henry
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UCL, Dept Genet Evolut & Environm, Gower St, London WC1E 6BT, EnglandUCL, Dept Genet Evolut & Environm, Gower St, London WC1E 6BT, England
Ferguson-Gow, Henry
Yang, Ziheng
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UCL, Dept Genet Evolut & Environm, Gower St, London WC1E 6BT, EnglandUCL, Dept Genet Evolut & Environm, Gower St, London WC1E 6BT, England
Yang, Ziheng
Goswami, Anjali
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UCL, Dept Genet Evolut & Environm, Gower St, London WC1E 6BT, England
UCL, Dept Earth Sci, Gower St, London WC1E 6BT, England
Nat Hist Museum, Fac Life Sci, Cromwell Rd, London SW9 5DJ, EnglandUCL, Dept Genet Evolut & Environm, Gower St, London WC1E 6BT, England