QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS FOR N-[(N',N'-DISUBSTITUTED-AMINO)ACETYL]ARYLAMINES FOR LOCAL-ANESTHETIC ACTIVITY AND ACUTE TOXICITY

被引：16
|
作者：
HEYMANS, F
LETHERIZIEN, L
GODFROID, JJ
BESSIN, P
机构：
[1] UNIV PARIS 7,PHARMOCHIM MOLEC LAB,F-75221 PARIS 05,FRANCE
[2] CREPHAR,DEPT PHARMACOL,F-91380 CHILLY MAZARIN,FRANCE
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1980年 / 23卷 / 02期
关键词：
D O I：
10.1021/jm00176a015
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：184 / 193
页数：10
相关论文
共 50 条
  • [21] SYNTHESIS OF SOME 4-HYDROXYPIPERAZINE AND N.N-DIBENZYLHYDROXYLAMINE ESTERS WITH POTENTIAL LOCAL-ANESTHETIC ACTIVITY
    RIDA, SM
    ISSA, AS
    BELTAGY, YA
    PHARMAZIE, 1978, 33 (11): : 711 - 713
  • [22] SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF N-ALKYL AND N,N'-DIALKYL SUBSTITUTED N,N'-DIARYLGUANIDINES AS NONCOMPETITIVE NMDA ANTAGONISTS
    REDDY, NL
    HU, LY
    FISCHER, JB
    MCBURNEY, RN
    WEBER, E
    HOLMES, DL
    WONG, ST
    PRASAD, R
    KEANA, JFW
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1991, 202 : 147 - MEDI
  • [23] QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS AND DESIGNED SYNTHESIS OF LARVICIDAL N,N'-DIBENZOYL-N-TERT-BUTYLHYDRAZINES AGAINST CHILO-SUPPRESSALIS
    NAKAGAWA, Y
    OIKAWA, N
    NISHIMURA, K
    UENO, T
    FUJITA, T
    PESTICIDE SCIENCE, 1995, 44 (01): : 102 - 105
  • [24] STRUCTURE-ACTIVITY-RELATIONSHIPS FOR HERBICIDAL N1-ARYL-N2-ALKYL THIOUREAS
    FRANKE, R
    KARANOV, E
    KANETI, J
    DOKLADI NA BOLGARSKATA AKADEMIYA NA NAUKITE, 1978, 31 (08): : 1051 - 1054
  • [25] STRUCTURE-ACTIVITY-RELATIONSHIPS OF N'-METHYL-N'-BETA-CHLOROETHYL-BENZALDEHYDE HYDRAZONES
    BRAUN, R
    HEFTER, E
    ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1977, 27-2 (11): : 2114 - 2117
  • [26] HERBICIDAL ACTIVITY OF N-BENZYLBUTANAMIDES .4. QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS OF THE HERBICIDAL N-BENZYLBUTANAMIDES AGAINST CYPERUS-ROTUNDUS
    KIRINO, O
    HASHIMOTO, S
    FURUZAWA, K
    TAKAYAMA, C
    OHSHIO, H
    JOURNAL OF PESTICIDE SCIENCE, 1983, 8 (03): : 315 - 319
  • [27] N-SUBSTITUTED DERIVATIVES OF EM 49 STRUCTURE-ACTIVITY-RELATIONSHIPS
    PLUSCEC, J
    SABO, EF
    NEUBECK, RO
    WEAVER, ER
    BASCH, H
    ONDETTI, MA
    JOURNAL OF ANTIBIOTICS, 1977, 30 (09): : 756 - 758
  • [28] STRUCTURE-ACTIVITY-RELATIONSHIPS IN N1-ACETYLDERIVATIVES OF SULFA DRUGS
    VAMPA, G
    PECORARI, P
    ALBASINI, A
    RINALDI, M
    MELEGARI, M
    BERTOLANI, D
    DEBENEDETTI, PG
    FARMACO-EDIZIONE SCIENTIFICA, 1982, 37 (10): : 701 - 710
  • [29] Synthesis and analgesic activity of N-(N-acetyl-L-amino-acyl)-5-methoxytryptamines
    Han, DM
    Wang, C
    Zhao, M
    Peng, SQ
    PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, 2000, 30 (01): : 39 - 47
  • [30] LOCAL-ANESTHETIC ACTIVITY AND ACUTE TOXICITY OF N-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1- AND 2-NAPHTHYLAMINES
    DREN, AT
    BOPP, BA
    EBERT, DM
    GEISZLER, AO
    HOLLAND, JB
    HORROM, BW
    DUNNIGAN, DA
    JOURNAL OF PHARMACEUTICAL SCIENCES, 1978, 67 (06) : 880 - 882
12345