1ST SYNTHESIS OF THE BENZO[F]PYRIDO[2',3'/3,4]PYRROLO[2,1-A][2,7]NAPHTHYRIDINE RING-SYSTEM

被引:15
|
作者
BRACHER, F
机构
[1] Institut für Pharmazeutische Chemie, Marburg, D-3550, Marbacher Weg 6, Lahn
关键词
D O I
10.1002/jhet.5570300128
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The lithiated pyridine 7 on reaction with methyl 4-methylquinoline-3-carboxylate (8) gave the ketone 9, which could be converted to the biaryl 11 via an effective two step anellation procedure. Treatment of 11 with dilute sulfuric acid resulted in an unexpected ring closure to give the title ring system.
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页码:157 / 159
页数:3
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