A CONCISE SYNTHESIS OF HYDROXYBUFURALOL

被引:0
|
作者
COLLIER, P [1 ]
SCHEINMANN, F [1 ]
STACHULSKI, AV [1 ]
机构
[1] SALFORD ULTRAFINE CHEM & RES LTD,SYNERGY HOUSE,GUILDHALL CLOSE,MANCHESTER SCI PK,MANCHESTER M15 6SY,ENGLAND
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中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The known ketoaldehyde 5, obtained in four steps from o-hydroxyacetophenone, is converted in three steps into the drug metabolite hydroxybufuralol 2 (diastereoisomers); previously 2 had been obtained in a total of thirteen steps from 4-bromophenol via bufuralol 1 itself.
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页码:312 / 313
页数:2
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