SYNTHESIS OF THIENOQUINOLINES .3. SYNTHESIS OF NOVEL 4-HYDRAZINO-TETRAHYDROQUINOLINO[3',2'-4,5]THIENO[3,2-D]PYRIMIDINE DERIVATIVES

被引：8
|
作者：
AWAD, IMA
ABDELRAHMAN, AE
BAKHITE, EA
机构：
[1] Chemistry Department, Assiut University, Assiut
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 1992年 / 69卷 / 3-4期
关键词：
METHYL S-TRIAZOLO-; ARYL S-TRIAZOLO-; TRIACETYL; HYDRAZONO- AND PYRAZOLYL-; TETRAHYDROQUINOLINOTHIENO-PYRIMIDINES;
D O I：
10.1080/10426509208040639
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Reaction of 4-hydrazino-11-(p-chlorophenyl)-7,8,9,10-tetrahydroquinolino[3',2':4,5]thieno[3,2-d]pyrimidine (2) with formic acid, acetic acid, diethylmalonate and/or carbon disulfide gave the corresponding s-triazolo derivatives (3, 4, 9) and (10) respectively. While acetylation of 2 yielded the triacetyl derivative (5). Also, condensation of 2 with aromatic aldehydes gave the hydrazones (6a-c) which cyclized easily into (7a-c). Moreover, acetylacetone was reacted with 2 to furnish the pyrazole derivative (8). The structural formula of these compounds was confirmed by elemental and spectral analyses data.
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页码：213 / 218
页数：6
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