SYNTHESIS OF DEMETHYLALLOSAMIDIN, A YEAST CHITINASE INHIBITOR - USE OF DISACCHARIDE GLYCOSYL DONOR CARRYING NOVEL NEIGHBORING GROUP

被引:20
|
作者
TAKAHASHI, S [1 ]
TERAYAMA, H [1 ]
KUZUHARA, H [1 ]
机构
[1] SAITAMA UNIV,FAC ENGN,DEPT FUNCT MAT SCI,URAWA,SAITAMA 338,JAPAN
关键词
D O I
10.1016/S0040-4039(00)73136-4
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
In the synthesis of novel pseudotrisaccharide called demethylallosamidin, a thioglycoside carrying the 2-acetamido group served as an efficient glycosyl donor through undergoing specific N,O-isopropylidenation at the 2- and 3-positions which prohibits oxazoline ring formation during the glycosidation reaction.
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页码:4149 / 4152
页数:4
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