First synthesis of hunterioside, a novel disaccharide carrying monoterpenoid indole alkaloid, by assembly of three components, tryptamine, secologanin, and a newly-developed glucosyl donor.

被引：4

作者：

Ohmori, O ^{[1
]}

Takayama, H ^{[1
]}

Aimi, N ^{[1
]}

机构：

[1] Chiba Univ, Fac Pharmaceut Sci, Res Ctr Med Resources, Inage Ku, Chiba 2638522, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 27期

关键词：

alkaloids; indole; glycoside; glycosidation;

D O I：

10.1016/S0040-4039(99)00928-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The novel structure of hunterioside, the first example of monoterpenoid indole alkaloids carrying a disaccharide, was confirmed by chemical synthesis starting from tryptamine, secologanin, and a newly-developed gulucosyl donor, which selectively gives alpha-gluco type glycosidic linkage in the reaction with a secologanin derivative. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：5039 / 5042

页数：4