SYNTHESIS OF ALL 4 ISOMERS OF DISPARLURE USING OSMIUM-CATALYZED ASYMMETRIC DIHYDROXYLATION

被引：66

作者：

KEINAN, E

SINHA, SC

SINHABAGCHI, A

WANG, ZM

ZHANG, XL

SHARPLESS, KB

机构：

[1] SCRIPPS RES INST, DEPT MOLEC BIOL, LA JOLLA, CA 92037 USA

[2] TECHNION ISRAEL INST TECHNOL, DEPT CHEM, IL-32000 HAIFA, ISRAEL

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 43期

关键词：

D O I：

10.1016/S0040-4039(00)79002-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(+)-Disparlure, the sex attractant emitted by the female gypsy moth, Porthetria dispar (L.), and its (-)-enantiomer were synthesized in 43% yield and >99% ee, starting from undecanal and using the asymmetric dihydroxylation (AD) reaction. Similarly, the two transisomers of disparlure were synthesized in 51% yield and 95% ee.

引用

页码：6411 / 6414

页数：4

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