HUMAN CHORIONIC-GONADOTROPIN AND ALPHA-FETOPROTEIN LEVELS IN MATCHED SAMPLES OF AMNIOTIC-FLUID, EXTRAEMBRYONIC CELOMIC FLUID, AND MATERNAL SERUM IN THE 1ST TRIMESTER OF PREGNANCY

被引：45
|
作者：
WATHEN, NC [1 ]
CASS, PL [1 ]
KITAU, MJ [1 ]
CHARD, T [1 ]
机构：
[1] HOMERTON HOSP,LONDON EC1A 7BE,ENGLAND
来源：
PRENATAL DIAGNOSIS | 1991年 / 11卷 / 03期
关键词：
HUMAN CHORIONIC GONADOTROPIN; ALPHA-FETOPROTEIN; AMNIOTIC FLUID; EXTRAEMBRYONIC COELOM; 1ST-TRIMESTER AMNIOCENTESIS;
D O I：
10.1002/pd.1970110303
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Separately identified samples of amniotic fluid and extraembryonic coelomic fluid obtained by high resolution transvaginal ultrasound-guided amniocentesis from 32 women between 7 and 12 weeks of pregnancy were analysed for human chorionic gonadotrophin (hCG) and alpha-fetoprotein (AFP). There was a highly significant difference between the hCG levels in amniotic fluid (median level 6.3 U/ml; range 1.6-310.0 U/ml) and those in extraembryonic coelomic fluid (median level 400.0 U/ml; range 135.0-2250.0 U/ml) (p < 0.001; Mann-Whitney U-test). The levels of AFP were very similar in amniotic fluid (median 26.0 kU/ml; range 10.0-116.5 kU/ml) and extraembryonic coelomic fluid (median level 24.1 kU/ml; range 12.4-94.4 kU/ml).
引用
收藏
页码：145 / 151
页数：7
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