Diabetes mellitus and cognitive decline

被引：0
|
作者：
Iglseder, Bernhard [1 ]
机构：
[1] Paracelsus Medizin Privatuniv, Univ Klin Geriat, Christian Doppler Klin, Ignaz Harrer Str 79, A-5020 Salzburg, Austria
来源：
WIENER MEDIZINISCHE WOCHENSCHRIFT | 2011年 / 161卷 / 21-22期
关键词：
Diabetes mellitus; cognitive decline; dementia; hyperglycemia; hypoglycemia;
D O I：
10.1007/s10354-011-0003-x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
From large epidemiological studies, it has been demonstrated that diabetes mellitus is a risk factor for cognitive decline: Compared to healthy controls, patients with diabetes perform worse on cognitive tests, they experience a pronounced cognitive decline over time and have a higher incidence of dementia. Mechanisms contributing to cognitive decline include vascular damage, negative consequences of hypo- and hyperglycemia, and various dysfunctions in insulin action, summarized as insulin resistance. Possible targets for prevention and treatment of cognitive decline have attracted scientific attention.
引用
收藏
页码：524 / 530
页数：7
相关论文
共 50 条
  • [31] DIABETES MELLITUS AND COGNITIVE DECLINE: SCREENING SCALES ARE NOT SENSITIVE ENOUGH IN EARLY STAGES OF DISEASE
    Kal'bus, O.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2011, 18 : 418 - 418
  • [32] Diabetes, aging, and cognitive decline
    Ryan, CM
    [J]. NEUROBIOLOGY OF AGING, 2005, 26 : S21 - S25
  • [33] The impact of diabetes mellitus on cognitive decline in the oldest of the old: a prospective population-based study
    van den Berg, E.
    de Craen, A. J. M.
    Biessels, G. J.
    Gussekloo, J.
    Westendorp, R. G. J.
    [J]. DIABETOLOGIA, 2006, 49 (09) : 2015 - 2023
  • [34] The impact of diabetes mellitus on cognitive decline in the oldest of the old: a prospective population-based study
    E. van den Berg
    A. J. M. de Craen
    G. J. Biessels
    J. Gussekloo
    R. G. J. Westendorp
    [J]. Diabetologia, 2006, 49 : 2015 - 2023
  • [35] A combination of midlife diabetes mellitus and the apolipoprotein E ε4 allele increase risk for cognitive decline
    Lee, Boung Chul
    Choe, Young Min
    Suh, Guk-Hee
    Choi, Ihn-Geun
    Lee, Jun Ho
    Kim, Hyun Soo
    Hwang, Jaeuk
    Yi, Dahyun
    Kim, Jee Wook
    [J]. FRONTIERS IN AGING NEUROSCIENCE, 2022, 14
  • [36] Type 2 diabetes mellitus, brain atrophy and cognitive decline in older people: a longitudinal study
    Callisaya, Michele L.
    Beare, Richard
    Moran, Chris
    Thanh Phan
    Wang, Wei
    Srikanth, Velandai K.
    [J]. DIABETOLOGIA, 2019, 62 (03) : 448 - 458
  • [37] Type 2 diabetes mellitus, brain atrophy and cognitive decline in older people: a longitudinal study
    Michele L. Callisaya
    Richard Beare
    Chris Moran
    Thanh Phan
    Wei Wang
    Velandai K. Srikanth
    [J]. Diabetologia, 2019, 62 : 448 - 458
  • [38] Diabetes mellitus and cognitive aging
    Korkina, MV
    Elfimova, EV
    [J]. ZHURNAL NEVROPATOLOGII I PSIKHIATRII IMENI S S KORSAKOVA, 2004, 104 (03): : 80 - 84
  • [39] Cognitive dysfunction and diabetes mellitus
    Kodl, Christopher T.
    Seaquist, Elizabeth R.
    [J]. ENDOCRINE REVIEWS, 2008, 29 (04) : 494 - 511
  • [40] Diabetes mellitus and cognitive impairment
    Surkova, E., V
    Tanashyan, M. M.
    Bespalov, A., I
    Naminov, A., V
    [J]. TERAPEVTICHESKII ARKHIV, 2019, 91 (10): : 112 - 118
12345