Diabetes mellitus and cognitive decline

被引：0
|
作者：
Iglseder, Bernhard [1 ]
机构：
[1] Paracelsus Medizin Privatuniv, Univ Klin Geriat, Christian Doppler Klin, Ignaz Harrer Str 79, A-5020 Salzburg, Austria
来源：
WIENER MEDIZINISCHE WOCHENSCHRIFT | 2011年 / 161卷 / 21-22期
关键词：
Diabetes mellitus; cognitive decline; dementia; hyperglycemia; hypoglycemia;
D O I：
10.1007/s10354-011-0003-x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
From large epidemiological studies, it has been demonstrated that diabetes mellitus is a risk factor for cognitive decline: Compared to healthy controls, patients with diabetes perform worse on cognitive tests, they experience a pronounced cognitive decline over time and have a higher incidence of dementia. Mechanisms contributing to cognitive decline include vascular damage, negative consequences of hypo- and hyperglycemia, and various dysfunctions in insulin action, summarized as insulin resistance. Possible targets for prevention and treatment of cognitive decline have attracted scientific attention.
引用
收藏
页码：524 / 530
页数：7
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